Efecto de un protocolo de ejercicio por cuatro semanas sobre el peso corporal y la glucemia en rata Wistar

Abstract

Tissue glucose requirements augment during exercise, particularly in skeletal muscle. Glucose levels rise during moderate intensity exercise (60-75% VO_2máx) due to an increase in the glucagon-insulin relationship (Engler, 2006). In this study we determined the effect of aerobic resistance exercise during four weeks on the body weight and blood sugar levels of Wistar rats. Experimental animals received training in a treadmill (Modular Enclosed Treadmill; Columbus Instrument, Columbus, OH, USA) with zero degrees of inclination and a 10 mV electric device incorporated. The exercise protocol was applied in 30 min sessions per day at a velocity of 10 m/min. with a frequency of 5 times a week for 4 weeks. Body weights and blood sugar levels were measured. At 12 hour fasting oral glucose tolerance curve (OGTC) was performed before and after the 4 weeks of exercise. The differences between the groups were analyzed using Student´s t tests, a p ≤ 0.05 was considered significant. After 4 weeks of training, the groups showed no significant differences in their body weights 262.0 ± 31.78 at the beginning, and 292.01 ± 35.62 g at the end of 4 weeks in the control group vs. 282.75 ± 25.91 g at the beginning, and 301.47 ± 31.38 g at the end of 4 weeks in the trained rats; p > 0.05). Similarly, blood glucose levels before and after 4 weeks of application of the exercise protocol were not significantly modified between the groups (73.5 ± 3.8 and 83.5 ± 2.38 g/dL in control group vs. 91.0 ± 7.43 and 85.7 ± 7.0 g/dL in the trained animals; p > 0.05). Likewise, the OGTC was comparable in both groups, before and after the application of the exercise protocol.